报告题目: Dissecting neural circuits for adult hippocampal neurogenesis
报告人/ Speaker:
Juan Song, PhD
Associate Professor
Jeffery Houpt Distinguished Investigator
Department of Pharmacology and Neuroscience Center
University of North Carolina, Chapel Hill
时间/Date:2019年12月17日09:00——10:00
地点/Location:闵行校区生物药学楼1-105
邀请人:李卫东教授(liwd@sjtu.edu.cn)
报告人简介/CV:
Juan Song is an Associate Professor in the Department of Pharmacology at UNC-Chapel Hill and Member of the Neuroscience Center. Dr. Song was a graduate student at UC-Berkeley and earned a Ph.D. in Neuroscience in 2007. As a postdoctoral fellow in Dr. Hongjun Song’s lab at Johns Hopkins University from 2007 to 2013, she pioneered the studies on how distinct neural circuits regulate neural stem cells and hippocampal neurogenesis (Song et al., Nature 2012; Song et al., Nature Neuroscience 2013). Building upon that work, Dr. Song leads a research team at UNC to investigate the mechanisms underlying regulation and function of adult hippocampal neurogenesis (Bao et al., Cell Stem cell 2017, Yeh et al., Neuron 2018). Among her many awards and honors, Dr. Song has been named as Jeffery Houpt Distinguished Investigator (UNC), and has received numerous prestigious awards, including a Yong Investigator Award from Brain and Behavior Foundation, a Janett Rosenberg Trubatch Career Development Award from Society for Neuroscience, and a Hettleman Prize for Artistic and Scholarly Achievement by Young Faculty.
报告摘要/Abstract:
Research in my lab is focused on understanding the mechanisms underlying regulation and function of adult hippocampal neurogenesis. Using a combination of sophisticated tools, my group is unravelling the neuronal circuitry and signaling mechanisms that regulate neural stem cells and subsequent hippocampal neurogenesis. In addition, my group is investigating how circuit- and behavior-level information-processing properties are remodeled, through the integration of new neurons into existing neuronal circuits. In my seminar, I will cover these aspects by talking about how distinct neural circuits regulate adult hippocampal neurogenesis and how dysregulated adult-born neurons contribute to brain-wide network abnormalities during the memory process.