Associate Professor of Shanghai Jiao Tong University, PI of Bio-X Institutes. Dr. Ping received his B.Sc. (2000-2004) and Ph.D. (2004-2009) in Biology from Fudan University. He pursued postdoctoral training at Harvard Medical School and Colorado State University (2009-2012). Dr. Ping joined Shanghai Jiao Tong University in 2013. His works were published in Nature Neuroscience, Journal of Physiology, PloS One, etc.

Understanding the pathological mechanisms of some neurological/mental diseases, such as Alzheimer’s disease and Schizophrenia. By using Drosophila (fruit fly) as animal model and employing the powerful fly genetics to find out genetic manipulations that can cause, suppress or enhance the disease phenotypes.

1.Ping Y and Tsunoda (2012). Homeostatic plasticity in Drosophila central neurons, and implications in human diseases. Fly 1;6(3).

2.Ping Y & Tsunoda S (2012). Inactivity-Induced Increase in nAChRs Up-Regulates Shal K+ Channels to Stabilize Synaptic Potentials. Nat Neurosci 15:90-97.

3.Ping Y, Waro G, Licursi A, Smith S, Vo-Ba DA, Tsunoda S (2011) Shal/K(v)4 channels are required for maintaining excitability during repetitive firing and normal locomotion in Drosophila. PLoS One 6:e16043.

4.Yang XF, Miao Y, Ping Y, Wu HJ, Yang XL, Wang Z (2011) Melatonin inhibits tetraethylammonium-sensitive potassium channels of rod ON type bipolar cells via MT2 receptors in rat retina. Neuroscience 173:19-29.

5.Ping Y, Huang H, Zhang XJ, Yang XL (2008) Melatonin potentiates rod signals to ON type bipolar cells in fish retina. J Physiol 586:2683-2694.

6.Shen Y, Chen L, Ping Y, Yang XL (2005) Glycine modulates the center response of ON type rod-dominant bipolar cells in carp retina. Brain Res Bull 67:492-497.

# Contributed equally to the paper * Corresponding author

(1) Jiang Bian*; Yi-qi Liu*; et al; Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands, European Journal of Medicinal Chemistry, 2021, 226(113887)

(2) Jiang Bian; Lihui Zhang; et al; Histone Deacetylase Inhibitors: Potent Anti-Leukemic Agents, Current Medicinal Chemistry, 2015.春季, 22(17): 2065-2074

(3) Yanfei Chen*; Jiang Bian*; et al; Design, Synthesis and Identification of N, N-Dibenzylcinnamamide(DBC) Derivatives as Novel Ligands for α-synuclein Fibrils by SPR Evaluation System, Bioorganic & Medicinal Chemistry, 2020, 28(7)(115358)

(4) Shenqing Zhang*; Hui Dong*; Jiang Bian*; Dan Li; Cong Liu; Targeting amyloid proteins for clinical diagnosis of neurodegenerative diseases, Fundamental Research, 2023(3): 505-519

(5) Chenyang Qiu*; Ruonan Wei*; Jiang Bian*; Xin Lin; Tengfei Bai; Jie He; Xiaomin Guo; YongChu; Novel 4-triazole phenyl amide (4-TPA) molecules: Potent promoters of α-synuclein fibril disassembly, European Journal of Medicinal Chemistry, 2024, 273(5)