My group develops novel computational methods and combines evolutionary biology with medical genetics to pursue primate evolutionary medicine. I have received the Xplorer Prize, Shanghai Overseas High-Level Talent, JSPS Special Research Fellowship, and Shanghai Pujiang Talent Program support. I currently lead projects in several domestic and international primate research alliances. My major findings have been published as corresponding author in Nature, Cell, Nature Methods, Genome Biology, Current Biology, etc. I serve on the editorial board of Genome Biology.

1. Mechanisms of structural variation in primate adaptive evolution and the origin of human genetic diseases
2. Genomic mechanisms of speciation, divergence, adaptation, and diversification

    1. Zhang, S., Xu, N., Fu, L., Yang, X., Li, Y., Yang, Z., ... Sun, Q.* & Mao, Y.* (2025). Integrated analysis of the complete sequence of a macaque genome. Nature.

    2. Mao, Y.*, Harvey, W. T., Porubsky, D., Munson, K. M., Hoekzema, K., Lewis, A. P., ... & Eichler, E. E.* (2024). Structurally divergent and recurrently mutated regions of primate genomes. Cell.

    3. Yang, Z., Zhang, L., Jiang, X., Yang, X., Ma, K., Yoo, D., ... & Mao, Y.* (2026). Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation. Cell Genomics, 6(1).

    4. Yang, X., Wang, X., Zou, Y. ... Mao Y.* (2023). Characterization of large-scale genomic differences in the first complete human genome. Genome Biology, 24, 157 .

    5. Ma, K., Yang, X., & Mao, Y.* (2025). Advancing evolutionary medicine with complete primate genomes and advanced biotechnologies. Trends in Genetics, 41(3), 201-217.

#并列第一作者 *通讯作者

1. Ma KY#,Yang XY#, Mao YF. Advancing evolutionary medicine with complete primate genomes and advanced biotechnologies[J].Trends in Genetics, 2024.（Cover Story）

2. Yang XY, Mao YF, Wang XK., Ma DN, Xu Z, Gong N, ... & Li WD*. (2023). Population genetics of marmosets in Asian primate research centers and loci associated with epileptic risk revealed by whole-genome sequencing. Zoological Research, 44(5), 837.

3. Yang XY#, Wang XK#, Zou YW, Zhang SL, Xia MY, Fu LT, ... & Mao YF*. (2023). Characterization of large-scale genomic differences in the first complete human genome. Genome biology, 24(1), 157.

4. Yang XY#, Chen ZT#, Wang ZY, He G, Li ZQ, Shi YY, ... & Li WD*. (2022). A natural marmoset model of genetic generalized epilepsy. Molecular Brain, 15(1), 1-4.