香港研究资助局General Research Fund 项目主持人。2015年香港青年科学家奖获得者。近五年内，共发表9篇论文于国际各权威期刊，其中包括Nat. Struct. Mol. Biol., PNAS, Acc. Chem. Res. 等高影响因子刊物（均为第一作者），以及Dev. Cell.（共同通讯作者）等其它一流刊物。

将现代结构生物学、生物化学、细胞生物学技术进行有机结合；系统性地研究各类肌球蛋白在神经网络形成和发育过程中的详细作用机制; 重点关注大脑发育障碍相关的致病基因；为阐明多种人类遗传疾病（如遗传性耳聋及失明，肠道系统疾病等）的发病机理提供了结构和生化基础。

1. Wang H, Du H, Ren R, Du T, Lin L, Feng Z, Zhao D, Wei X, Zhai X, Wang H, Dong T, Sun JP, Wu H, Xu Z, Lu Q. Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation. Nat Commun. 2023 Mar 24;14(1):1657.

2. Ren D, Wei X, Lin L, Yuan F, Bi Y, Guo Z, Liu L, Ji L, Yang X, Han K, Yang F, Wu X, Li X, Yi Z, Xu Y, Cai C, Wang P, Li W, He L, Zhou D, Yu T, Shi Y, Lu Q*, He G*. A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity. Mol Psychiatry. 2022 Jun;27(6):2777-2786.

3. Huang Wang, Dange Zhao, Haibo Du, Xiaoyan Zhai, Shaoxuan Wu, Lin Lin, Zhigang Xu, Qing Lu; Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2. Biochem J 30 June 2022; 479 (12): 1393–1405.

4. Xiaoyan Zhai, Yuxin Shen, Xiujuan Zhang, Tianhao Li, Qing Lu, Zhigang Xu, FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Volume 1869, Issue 1, 2022, 119134, ISSN 0167-4889.

5. Lin L, Wang H, Ren D, Xia Y, He G*, Lu Q*. Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss. Front Cell Dev Biol. 2021 Apr 15;9:642666.

6.Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J*, Zhang R*. Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep. 2021 Feb 23;34(8):108770.

7.Song X, Feng J, Lan X, Tang X, Xu W, Shen J, Yu G, Jia J, Zhang H, Lu Q*, Wu S*. Generation and characterization of an iPSC line (SHCMDLi001-A) from a 12-year-old Chinese Han patient with TRAF7 syndrome and of an iPSC line (SHCMDLi002-A) from a control individual. Stem Cell Res. 2021 May;53:102377.

8. Jianchao Li, Yunyun He, Qing Lu, Mingjie Zhang, Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex, Developmental Cell, Volume 36, Issue 2, 2016, Pages 179-189, ISSN 1534-5807.

9. Lu Q, Li J, Ye F, Zhang M. Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling. Nat Struct Mol Biol. 2015 Jan;22(1):81-8.

#并列第一作者 *通讯作者